SPP1, secreted phosphoprotein 1, 6696

N. diseases: 824; N. variants: 13
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0334037
Disease: Intestinal metaplasia
Intestinal metaplasia
0.020 GeneticVariation phenotype BEFREE SPP1 polymorphisms predispose to IM development in H. pylori infected males. 28685609 2017
CUI: C0334037
Disease: Intestinal metaplasia
Intestinal metaplasia
0.020 AlteredExpression phenotype BEFREE For the H. pylori-infected patients, an increased OPN expression correlated with more severe chronic gastric inflammation (p < .001) and the presence of IM (OR: 2.6, 95% CI: 1.15-5.94, p = .02). 21585607 2011