SPP1, secreted phosphoprotein 1, 6696

N. diseases: 824; N. variants: 13
Disease: Carotid Atherosclerosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0577631
Disease: Carotid Atherosclerosis
Carotid Atherosclerosis 		0.030 Biomarker disease BEFREE OPN and OPG positively correlated with greater systolic blood pressure (SBP) values, HOMA-IR and HOMA-β, and with the presence of dyslipidemia and carotid atherosclerosis. 30132286 2019
CUI: C0577631
Disease: Carotid Atherosclerosis
Carotid Atherosclerosis 		0.030 Biomarker disease BEFREE Here, we investigated serum osteopontin (OPN) as a potential predictor of poor outcome in patients with severe carotid atherosclerosis. 29317141 2018
CUI: C0577631
Disease: Carotid Atherosclerosis
Carotid Atherosclerosis 		0.030 GeneticVariation disease BEFREE We demonstrated an important effect of the SPP1 rs4754 on subclinical markers of carotid atherosclerosis in subjects with T2DM; however, as demonstrated by the multiple linear regression analysis, neither rs4754 nor rs28357094 had an important impact on the progression of subclinical markers of carotid atherosclerosis in subjects with T2DM. 28990744 2018