SPP1, secreted phosphoprotein 1, 6696

N. diseases: 824; N. variants: 13
Disease: PATENT DUCTUS ARTERIOSUS 1 ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4282128
Disease: PATENT DUCTUS ARTERIOSUS 1
PATENT DUCTUS ARTERIOSUS 1 		0.060 Biomarker disease BEFREE Thus, the GLI2-OPN circuit is a driver of PDA cell plasticity that establishes and maintains an aggressive variant of this disease. 31134896 2019
CUI: C4282128
Disease: PATENT DUCTUS ARTERIOSUS 1
PATENT DUCTUS ARTERIOSUS 1 		0.060 AlteredExpression disease BEFREE Our aim was to examine the expression pattern of OPN splice variants a, b, and c in fine-needle aspirates and to determine their correlation with stage-adjusted pancreatic ductal adenocarcinoma (PDA) survival. 24548099 2014
CUI: C4282128
Disease: PATENT DUCTUS ARTERIOSUS 1
PATENT DUCTUS ARTERIOSUS 1 		0.060 AlteredExpression disease BEFREE OPNc and total OPN levels were correlated in the tissue from patients with invasive PDA. 21630219 2011
CUI: C4282128
Disease: PATENT DUCTUS ARTERIOSUS 1
PATENT DUCTUS ARTERIOSUS 1 		0.060 AlteredExpression disease BEFREE In this study, we explored the potential proinflammatory role of nicotine in PDA through studying its effect on the expression of monocyte chemoattractant protein (MCP)-1 and evaluated the role of OPN in mediating these effects. 20579680 2010
CUI: C4282128
Disease: PATENT DUCTUS ARTERIOSUS 1
PATENT DUCTUS ARTERIOSUS 1 		0.060 AlteredExpression disease BEFREE The levels of OPNc correlated well with higher expression levels of total OPN in the tissue and serum from patients with invasive PDA. 19628079 2009
CUI: C4282128
Disease: PATENT DUCTUS ARTERIOSUS 1
PATENT DUCTUS ARTERIOSUS 1 		0.060 Biomarker disease BEFREE Here, we investigated the potential molecular basis of nicotine's role in PDA through studying its effect on OPN. 19358273 2009