BRCA1, BRCA1 DNA repair associated, 672

N. diseases: 747; N. variants: 2600
Disease: Menopausal symptom ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0236075
Disease: Menopausal symptom
Menopausal symptom 		0.030 GeneticVariation phenotype BEFREE Sixty-six women carriers of the BRCA1/2 mutation who developed at least two moderate-to-severe menopausal symptoms after RRSO. 30222235 2019
CUI: C0236075
Disease: Menopausal symptom
Menopausal symptom 		0.030 GeneticVariation phenotype BEFREE Effects of bilateral salpingo-oophorectomy on menopausal symptoms and sexual functioning among women with a BRCA1 or BRCA2 mutation. 30414741 2019
CUI: C0236075
Disease: Menopausal symptom
Menopausal symptom 		0.030 GeneticVariation phenotype BEFREE This article analyzes the role of RRBSO in women with BRCA1/BRCA2 mutations with no personal history of breast cancer and the impact of hormone therapy on risk for breast and gynecological cancers if used after the procedure to alleviate the resulting menopausal symptoms. 27426853 2016