BRCA1, BRCA1 DNA repair associated, 672

N. diseases: 747; N. variants: 2600
Disease: Borderline ovarian tumour ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0862506
Disease: Borderline ovarian tumour
Borderline ovarian tumour 		0.040 Biomarker disease BEFREE Therefore, we conclude that borderline ovarian tumors are neither part of the BRCA1- nor the BRCA2- related tumor spectrum. 17386038 2007
CUI: C0862506
Disease: Borderline ovarian tumour
Borderline ovarian tumour 		0.040 Biomarker disease BEFREE Although the incidence of borderline ovarian tumors may not be increased in HBOC syndrome kindreds and those who carry cancer-associated BRCA1 and BRCA2 mutations, these individuals could be susceptible to malignant transformation of borderline lesions of the ovaries and peritoneum. 15516851 2004
CUI: C0862506
Disease: Borderline ovarian tumour
Borderline ovarian tumour 		0.040 GeneticVariation disease BEFREE To gain insight into these issues, we determined the rates of 185delAG-BRCA1 and 6174delT-BRCA2 mutations in patients with borderline ovarian tumors. 9665148 1998
CUI: C0862506
Disease: Borderline ovarian tumour
Borderline ovarian tumour 		0.040 Biomarker disease BEFREE These results suggest that inactivation of the BRCA1 gene may not be responsible for the development of borderline ovarian tumors and that another tumor suppressor gene, located centromeric to the BRCA1 gene, may play a role in sporadic ovarian cancer development. 8632895 1996