Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.050 Biomarker disease BEFREE Down-regulated of SREBP-1 in circulating leukocyte is a risk factor for atherosclerosis: a case control study. 31610782 2019
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.050 AlteredExpression disease BEFREE The CIH composite AGM could promote the progress of AS, which might be related to the modulation of the expression of SREBP-1-related molecular pathways. 30863480 2019
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.050 Biomarker disease BEFREE Conclusions- Our data demonstrated critical roles of SREBF1-miR-33b axis on both lipid profiles and macrophage phenotype remodeling and indicate that miR-33b is a promising target for treating atherosclerosis. 30354203 2018
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.050 GeneticVariation disease BEFREE Global tests revealed no main effects between SCAP, INSIG1, and SREBP1 haplotypes and progression of atherosclerosis (P = .87, P = .58, and P = .44). 24655714 2014
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.050 Biomarker disease BEFREE In contrast, bone marrow-specific SREBP-1 deficiency did not alter the development of atherosclerosis. 21546605 2011