Disease: Obesity ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity 		0.220 GeneticVariation disease BEFREE We identified a 3-locus interaction on obesity in GMDR analyses (P = 0.001), involving 3 genetic variants of INSIG2, SCAP, and SREBP2. 25028659 2014
CUI: C0028754
Disease: Obesity
Obesity 		0.220 Biomarker disease BEFREE We show here that sterol regulatory element-binding protein 2 (SREBP-2) and its target genes are induced in the adipose tissue of several models of rodent obesity, suggesting cholesterol imbalance in enlarged adipocytes. 11278795 2001
CUI: C0028754
Disease: Obesity
Obesity 		0.220 Biomarker disease RGD In contrast, immunoreactive SREBP2, which was very low in nuclear extracts from lean rats, was induced in obese rat fat cells. 9786926 1998