SRF, serum response factor, 6722

N. diseases: 147; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.020 Biomarker group BEFREE Previously, we demonstrated that an endothelial cell-specific ablation of the murine Serum Response Factor (Srf<sup>iECKO</sup>) results in blood brain barrier (BBB) breakdown and hemorrhagic stroke. 28473286 2017
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.020 Biomarker group BEFREE Integrative transcriptional and cell survival analyses showed that IRF4 functions mechanistically as a transcription activator of serum response factor (SRF) crucial to salvage neurons during stroke. 24510125 2014