|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Novel role of sex-determining region Y-box 7 (SOX7) in tumor biology and cardiovascular developmental biology.
|
31473269 |
2019 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
This study evaluated whether high-potency NAs (entecavir and tenofovir disoproxil fumarate [TDF]) reduce the risk of tumour recurrence more potently than low-potency NAs after curative treatment of hepatitis B virus (HBV)-related HCC.
|
29316069 |
2018 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Aberrant expression of different SOX (SRY-related high mobility group (HMG) box) genes has been observed in number of tumors but, little is known about their expression patterns in hematological malignancies, especially in acute myeloid leukemia (AML).
|
29428447 |
2018 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Almost no α-TOS release was found within 80 h, and release of 2-DG was sustained and slow within 72 h. The results of FR binding assay and fluorescence biodistribution revealed that TDF NPs could target FR highly expressed on tumor cell in vitro and in vivo.
|
28848348 |
2017 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Sex determining region Y‑box 7 (SOX7) is known to function as a tumor suppressor in a number of types of cancer; however, its role in liver and pancreatic carcinoma remains unclear.
|
28586005 |
2017 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Ullrich-Turner Syndrome and Tumor Risk: Is There Another Chance to Early Gonadectomy in Positive TSPY and SRY Patients?
|
25978024 |
2016 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Sex-determining region Y box 6 (SOX6) has been described as a tumor-suppressor gene in several cancers.
|
26119940 |
2016 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Sex determining region Y‑box 18 (SOX18) has been found to be overexpressed in several types of tumor.
|
26573263 |
2016 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
In addition, the relative expression of the SRY gene had a median 5.5 times larger in the tumor than in its periphery (range, 1.1-389.4).
|
26808509 |
2016 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The sex determining region Y (SRY)-box 5 (Sox5), runt-related transcription factor 3 (RUNX3), CCAAT displacement protein 1 (CUTL1), v-rel avian reticuloendotheliosis viral oncogene homolog (Rel)A, peroxisome proliferator-activated receptor γ isoform 2 (PPARγ2) and activating transcription factor 6 (ATF6) regulatory transcription factor binding sites were identified in the upstream (promoter) region of the RNPC1 gene, and may thus be involved in the effects of RNPC1 in tumors.
|
26046131 |
2015 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Sex-determining region Y (SRY)-box 1 (SOX1) as a member of the SOX gene superfamily is reported to function as a tumor suppressor in hepatocelluar cancer (HCC).
|
26191244 |
2015 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Bioinformatics analysis further revealed sex-determining region Y-box 7 (SOX7), a putative tumor suppressor, as a potential target of miR-492.
|
25407488 |
2015 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Many papers have shown that SRY (sex-determining region Y)-box (SOX) family genes serve as either tumor suppressor genes (TSGs) or oncogenes by regulating the Wnt signaling pathway in different cancers.
|
23927962 |
2013 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Identification of potential tumor differentiation factor (TDF) receptor from steroid-responsive and steroid-resistant breast cancer cells.
|
22130669 |
2012 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
SRY-box containing gene 17 (SOX17) was reported to be indispensable for embryonic development and a candidate tumor suppressor gene which antagonizes the canonical WNT/β-catenin signaling pathway in colorectal cancer.
|
20716954 |
2011 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
To determine the frequency of XY karyotypes among females with complete gonadal dysgenesis (CGD) and to investigate the frequency of both gonadal tumors and SRY mutations.
|
21982289 |
2011 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
SOX4, an oncogene belonging to the SRY-related high mobility group box family, was found to be overexpressed (P < 0.005) in endometrial tumors (n = 74) compared with uninvolved controls (n = 20).
|
19887623 |
2009 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
The father of the three children presented with hypospadias; cryptorchidism; testicular seminoma and oligoasthenozoospermia, an association termed testicular dysgenesis syndrome (TDS); and the SRY mutation in a mosaic state in the peripheral blood and the tumor.
|
19531589 |
2009 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
The patient (22-years-old) without an associated tumor did not have the cryptic deletion or mutation of SRY.
|
10459352 |
1999 |