Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019196
Disease: Hepatitis C
Hepatitis C
0.060 Biomarker disease BEFREE Anti-SSA/Ro and anti-SSB/La autoantibodies were detected in 12.8 and 9.7% of HCV-infected patients. 17992468 2008
CUI: C0019196
Disease: Hepatitis C
Hepatitis C
0.060 Biomarker disease LHGDN We found that La is essential for efficient HCV replication while PTB appears to partially repress replication. 15823607 2005
CUI: C0019196
Disease: Hepatitis C
Hepatitis C
0.060 Biomarker disease LHGDN La protein is a potent regulator of replication of hepatitis C virus in patients with chronic hepatitis C through internal ribosomal entry site-directed translation. 15685555 2005
CUI: C0019196
Disease: Hepatitis C
Hepatitis C
0.060 Biomarker disease LHGDN Hepatitis C virus internal ribosome entry site-mediated translation is stimulated by specific interaction of independent regions of human La autoantigen. 12540850 2003
CUI: C0019196
Disease: Hepatitis C
Hepatitis C
0.060 Biomarker disease BEFREE Hepatitis C virus internal ribosome entry site-mediated translation is stimulated by specific interaction of independent regions of human La autoantigen. 12540850 2003
CUI: C0019196
Disease: Hepatitis C
Hepatitis C
0.060 AlteredExpression disease BEFREE Interestingly, the expression of the autoantigen, La, which has been reported to enhance HCV-IRES-directed translation, was significantly reduced after the administration of IFN-alpha and poly(I)-poly(C) in a dose-dependent manner. 11786977 2002
CUI: C0019196
Disease: Hepatitis C
Hepatitis C
0.060 Biomarker disease BEFREE Finally, the binding of the La autoantigen to the HCV IRES element was specifically and efficiently competed by IRNA. 9621022 1998