BRCA2, BRCA2 DNA repair associated, 675

N. diseases: 656; N. variants: 3066
Disease: Breast Neoplasms, Male ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0242788
Disease: Breast Neoplasms, Male
Breast Neoplasms, Male 		0.100 GeneticVariation group LHGDN Similar prevalence of founder BRCA1 and BRCA2 mutations among Ashkenazi and non-Ashkenazi men with breast cancer: evidence from 261 cases in Israel, 1976-1999. 18158280 2008
CUI: C0242788
Disease: Breast Neoplasms, Male
Breast Neoplasms, Male 		0.100 Biomarker group LHGDN BRCA1/2 mutation analysis in male breast cancer families from North West England. 17636422 2008
CUI: C0242788
Disease: Breast Neoplasms, Male
Breast Neoplasms, Male 		0.100 GeneticVariation group LHGDN BRCA1/BRCA2 rearrangements and CHEK2 common mutations are infrequent in Italian male breast cancer cases. 17661168 2008
CUI: C0242788
Disease: Breast Neoplasms, Male
Breast Neoplasms, Male 		0.100 GeneticVariation group LHGDN BRCA2 gene mutations in Slovenian male breast cancer patients. 18439106 2008
CUI: C0242788
Disease: Breast Neoplasms, Male
Breast Neoplasms, Male 		0.100 GeneticVariation group LHGDN A carrier of both MEN1 and BRCA2 mutations: case report and review of the literature. 18036394 2007
CUI: C0242788
Disease: Breast Neoplasms, Male
Breast Neoplasms, Male 		0.100 GeneticVariation group LHGDN Association between the BRCA2 N372H variant and male breast cancer risk: a population-based case-control study in Tuscany, Central Italy. 17767707 2007
CUI: C0242788
Disease: Breast Neoplasms, Male
Breast Neoplasms, Male 		0.100 GeneticVariation group LHGDN Phenotypic features and genetic characterization of male breast cancer families: identification of two recurrent BRCA2 mutations in north-east of Italy. 16764716 2006
CUI: C0242788
Disease: Breast Neoplasms, Male
Breast Neoplasms, Male 		0.100 GeneticVariation group LHGDN Large genomic BRCA2 rearrangements and male breast cancer. 17113724 2006
CUI: C0242788
Disease: Breast Neoplasms, Male
Breast Neoplasms, Male 		0.100 Biomarker group BEFREE As such, BRCA2 can exert its tumor suppressor function, in part, by modulating androgen signaling, which has been shown to be antiproliferative in a subset of breast cancer cells and particularly implicated in male breast tumors. 12756300 2003
CUI: C0242788
Disease: Breast Neoplasms, Male
Breast Neoplasms, Male 		0.100 GeneticVariation group LHGDN Somatic mutations in the BRCA2 gene and high frequency of allelic loss of BRCA2 in sporadic male breast cancer. 11948477 2002