BRDT, bromodomain testis associated, 676

N. diseases: 17; N. variants: 3
Disease: Teratozoospermia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0403824
Disease: Teratozoospermia
Teratozoospermia 		0.010 Biomarker disease BEFREE Mutant mice that expressed truncated BRDT had impaired testicular histology with severely reduced sperm concentration and abnormal sperm morphology, while a model of knockout Brdt mice with no BRDT protein had complete meiotic arrest. 24865796 2014