ST13, ST13 Hsp70 interacting protein, 6767

N. diseases: 81; N. variants: 2
Disease: Colorectal Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.070 AlteredExpression disease BEFREE The transcript level of ST13 in different CRC cell lines was evaluated by quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR). 23125081 2012
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.070 Biomarker disease BEFREE In addition to the CRC specificity, the antitumor effect of Ad·(ST13)·CEA·E1A(Δ24) was also excellent and got nearly complete inhibition (not eradication) of CRC xenograft since ST13 was an effective antitumor gene with less toxicity, and a Chinese patent (No. 23077639 2012
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.070 Biomarker disease BEFREE ST13, a co-factor of heat shock protein, has shown potential antitumor efficacy for colorectal cancer in our previous study. 20512919 2010
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.070 Biomarker disease BEFREE Potent antitumor activity of double-regulated oncolytic adenovirus-mediated ST13 for colorectal cancer. 19298599 2009
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.070 AlteredExpression disease BEFREE In summary, overexpressed ST13 as mediated by oncolytic adenovirus could exert potent antitumor activity via the intrinsic apoptotic pathway and has the potential to become a novel therapeutic for colorectal cancer gene therapy. 18355116 2008
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.070 GeneticVariation disease BEFREE The HIP gene encoding a heparin/heparan sulfate interacting protein is mutated in metastatic human colorectal cancer. 12632100 2003
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.070 Biomarker disease BEFREE HIP is a candidate marker of abnormal cell growth in the colon and a prognostic marker for colorectal carcinoma. 10383165 1999