ST13, ST13 Hsp70 interacting protein, 6767

N. diseases: 81; N. variants: 2
Disease: Malignant neoplasm of colon and/or rectum ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.050 Biomarker disease BEFREE Although many studies on CEA promoter and ST13 gene were reported but no construct has been performed to combine both of them as a new strategy for colorectal cancer (CRC) specific therapy. 23077639 2012
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.050 Biomarker disease BEFREE ST13, a co-factor of heat shock protein, has shown potential antitumor efficacy for colorectal cancer in our previous study. 20512919 2010
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.050 Biomarker disease BEFREE Potent antitumor activity of double-regulated oncolytic adenovirus-mediated ST13 for colorectal cancer. 19298599 2009
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.050 AlteredExpression disease BEFREE In summary, overexpressed ST13 as mediated by oncolytic adenovirus could exert potent antitumor activity via the intrinsic apoptotic pathway and has the potential to become a novel therapeutic for colorectal cancer gene therapy. 18355116 2008
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.050 GeneticVariation disease BEFREE The HIP gene encoding a heparin/heparan sulfate interacting protein is mutated in metastatic human colorectal cancer. 12632100 2003