ST14, suppression of tumorigenicity 14, 6768

N. diseases: 170; N. variants: 9
Disease: Hemophilia A ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019069
Disease: Hemophilia A
Hemophilia A 		0.100 Biomarker disease BEFREE Polymorphism distribution of Int13, Int22, and St14 VNTRs in a Mexican population and their application in carrier diagnosis of hemophilia A. 15307098 2004
CUI: C0019069
Disease: Hemophilia A
Hemophilia A 		0.100 GeneticVariation disease BEFREE Carrier detection and prenatal diagnosis of hemophilia A in a Korean population by PCR-based analysis of the BclI/intron 18 and St14 VNTR polymorphisms. 10944851 2000
CUI: C0019069
Disease: Hemophilia A
Hemophilia A 		0.100 Biomarker disease BEFREE Rapid polymerase chain reaction analysis of St14 (DXS52) VNTR: carrier detection of hemophilia A. 9311183 1997
CUI: C0019069
Disease: Hemophilia A
Hemophilia A 		0.100 Biomarker disease BEFREE The results obtained from a comparative analysis between phenotypic bioassays as the ratio of factor VIII: C clotting activity to factor VIII: C-related antigen, and DNA haplotypes from RFLP's TaqI/St14 and BclI/F8A in 12 hemophilia A (HeA) families are described. 1358771 1992
CUI: C0019069
Disease: Hemophilia A
Hemophilia A 		0.100 GeneticVariation disease BEFREE Sixty-five individuals belonging to 16 argentinian families of hemophilia A were studied using the St 14 probe (DXS52 locus). 1973342 1990
CUI: C0019069
Disease: Hemophilia A
Hemophilia A 		0.100 GeneticVariation disease BEFREE Her father had no clinical or biochemical signs of haemophilia A. RFLP-analysis using DX13 and St14 probes each elicited one allele (5.8 and 3.4 kb, respectively) segregating along with the affected F VIII gene from the hemizygous grandfather to both his daughters and further to the haemophilic female child. 2564325 1989
CUI: C0019069
Disease: Hemophilia A
Hemophilia A 		0.100 Biomarker disease BEFREE The combination of the Bcll, Xbal, and Taql/St14 RFLPs gave 100% carrier detection in the hemophilia A families analyzed. 2900870 1988
CUI: C0019069
Disease: Hemophilia A
Hemophilia A 		0.100 Biomarker disease BEFREE They include a new Bell restriction fragment length polymorphism (RFLP) detected by the probe St14-1 (DXS52) and which may therefore be of diagnostic use in hemophilia A families. 3502701 1987
CUI: C0019069
Disease: Hemophilia A
Hemophilia A 		0.100 Biomarker disease BEFREE Two events of recombination were found between the St14 and the haemophilia A locus in 51 informative meioses. 2885943 1987
CUI: C0019069
Disease: Hemophilia A
Hemophilia A 		0.100 GeneticVariation disease BEFREE Postulating that the combined use of all the available intragenic and extragenic markers can render such diagnoses more frequently feasible and more reliable, we carried out ten first-trimester prenatal diagnoses in male fetuses at risk for hemophilia A by DNA analysis of chorionic villus employing in combination the intragenic Bcl I polymorphism and the St 14 (DXS 52) or DX 13 (DXS 15) extragenic probes. 3127923 1987
CUI: C0019069
Disease: Hemophilia A
Hemophilia A 		0.100 Biomarker disease BEFREE The haplotypes generated by two extra-genic RFLPs, at DXS52 (St14/Taq1) and DXS15 (DX13/BglII), and one intragenic RFLP in F8C (647/BclI) indicated that: she was not a carrier; the case of hemophilia resulted from a de novo mutation in a grandfather's gamete. 2877941 1986
CUI: C0019069
Disease: Hemophilia A
Hemophilia A 		0.100 Biomarker disease BEFREE If a small risk of misclassification due to crossover between the test and the disease loci is accepted, this DNA marker should allow first-trimester prenatal diagnosis of hemophilia A. Segregation analysis with St14 may thus represent a major improvement in genetic counseling for hemophilia A. 2983207 1985