Disease: Herpes Simplex Infections ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019348
Disease: Herpes Simplex Infections
Herpes Simplex Infections 		0.030 GeneticVariation group BEFREE In primary macrophages and fibroblasts, we found that STAT1 R274W had no appreciable effect on cell-intrinsic immunity against herpes simplex virus 1 (HSV-1) or gammaherpesvirus 68 (γHV68) infection. 31315996 2019
CUI: C0019348
Disease: Herpes Simplex Infections
Herpes Simplex Infections 		0.030 Biomarker group BEFREE STAT1 activation in response to oHSV infection was found to associate with diminished Δγ134.5 oHSVs replication and spread. 26883073 2016
CUI: C0019348
Disease: Herpes Simplex Infections
Herpes Simplex Infections 		0.030 Biomarker group BEFREE Children with germline mutations in Toll-like receptor 3 (TLR3), UNC93B1, TNF receptor-associated factor 3, and signal transducer and activator of transcription 1 are prone to herpes simplex virus-1 encephalitis, owing to impaired TLR3-triggered, UNC-93B-dependent, IFN-α/β, and/or IFN-λ-mediated signal transducer and activator of transcription 1-dependent immunity. 21722947 2011