Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0021400
Disease: Influenza
Influenza
0.330 Biomarker disease BEFREE Thus, our data demonstrated a critical role for p-STAT1 in influenza virus replication and inflammatory responses. 31493649 2019
CUI: C0021400
Disease: Influenza
Influenza
0.330 AlteredExpression disease BEFREE Influenza viral HA strongly decreased cellular sensitivity to type II IFNs, as it suppressed the activation of STAT1 and the induction of IFN-γ-stimulated genes in response to exogenously supplied recombinant IFN-γ. 29343571 2018
CUI: C0021400
Disease: Influenza
Influenza
0.330 Biomarker disease BEFREE Influenza was associated with overexpression of 20 genes, including those encoding the cytokines tumor necrosis factor and IL-12; the kinases MEK, TBK-1, and STAT-1; the apoptosis proteins caspase-8 and caspase-10; the influenza double-stranded RNA receptor RIG-I and its downstream effector MAVS; and pyrin, an IFN-stimulated protein involved in influenza resistance. 24641803 2014
CUI: C0021400
Disease: Influenza
Influenza
0.330 Biomarker disease CTD_human A host transcriptional signature for presymptomatic detection of infection in humans exposed to influenza H1N1 or H3N2. 23326326 2013