STAT3, signal transducer and activator of transcription 3, 6774
N. diseases: 1193; N. variants: 57
Source: ALL
| Disease | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year |
|---|---|---|---|---|---|---|---|
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0.070 | Biomarker | disease | BEFREE | Docosahexaenoic acid inhibits Helicobacter pylori-induced STAT3 phosphorylation through activation of PPARγ. | 27079734 | 2016 |
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0.070 | Biomarker | disease | BEFREE | Jak1/Stat3 is an upstream signaling of NF-κB activation in Helicobacter pylori-induced IL-8 production in gastric epithelial AGS cells. | 25837197 | 2015 |
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0.070 | GeneticVariation | disease | BEFREE | STAT3 polymorphism and Helicobacter pylori CagA strains with higher number of EPIYA-C segments independently increase the risk of gastric cancer. | 26186918 | 2015 |
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0.070 | Biomarker | disease | BEFREE | Bidirectional regulation between TMEFF2 and STAT3 may contribute to Helicobacter pylori-associated gastric carcinogenesis. | 24996057 | 2015 |
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0.070 | Biomarker | disease | BEFREE | A positive feedback loop between STAT3 and cyclooxygenase-2 gene may contribute to Helicobacter pylori-associated human gastric tumorigenesis. | 24127267 | 2014 |
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0.070 | Biomarker | disease | BEFREE | The induction of MCP-1 and iNOS was inhibited by both the Jak2/Stat3 inhibitor AG490 and RGE in Helicobacter pylori-infected cells. | 24055641 | 2013 |
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0.070 | Biomarker | disease | BEFREE | Helicobacter pylori cytotoxin-associated gene A activates the signal transducer and activator of transcription 3 pathway in vitro and in vivo. | 19147578 | 2009 |