Disease: Progression of prostate cancer ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1739135
Disease: Progression of prostate cancer
Progression of prostate cancer 		0.020 Biomarker disease BEFREE Risk estimates for seven SNPs varied significantly according to disease aggressiveness (P(homogeneity) < 0.05), with SNPs in AKT1, PIK3R1, and STAT3 independently associated with more aggressive PC; OR = 5.1 (95% CI: 2.29-11.40, P(trend) = 3.8 × 10(-5)) for carriers of all high-risk genotypes. 21430300 2011
CUI: C1739135
Disease: Progression of prostate cancer
Progression of prostate cancer 		0.020 Biomarker disease BEFREE Previous studies demonstrated that constitutively activated Stat3 plays an important role in the development and progression of prostate cancer by promoting cell proliferation and protecting against apoptosis. 15264241 2004