Disease: Mastocytosis, Systemic ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic 		0.050 Biomarker disease BEFREE Together, our data show that CD44 is a RAS-MEK/STAT5-driven MC invasion receptor that correlates with the aggressiveness of SM. 30018080 2018
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic 		0.050 Biomarker disease BEFREE The present article provides an overview of our current knowledge about the critical role of AKT and STAT5 in the pathophysiology of chronic myeloid leukemia and systemic mastocytosis and on their potential value as therapeutic targets in these neoplasms. 24598853 2014
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic 		0.050 GeneticVariation disease BEFREE Identification of oncostatin M as a STAT5-dependent mediator of bone marrow remodeling in KIT D816V-positive systemic mastocytosis. 21457934 2011
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic 		0.050 GeneticVariation disease BEFREE We examined the expression of pSTAT5 in neoplastic mast cells in systemic mastocytosis and asked whether the disease-related oncoprotein KIT D816V is involved in STAT5 activation. 19893034 2009
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic 		0.050 Biomarker disease BEFREE Detection of phospho-STAT5 in mast cells: a reliable phenotypic marker of systemic mast cell disease that reflects constitutive tyrosine kinase activation. 17662084 2007