STIM1, stromal interaction molecule 1, 6786

N. diseases: 247; N. variants: 23
Disease: Kaposi's sarcoma classical type ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0279084
Disease: Kaposi's sarcoma classical type
Kaposi's sarcoma classical type 		0.010 Biomarker disease BEFREE Based on the previous discovery of STIM1 deficiency in a single family with a severe T cell immunodeficiency and the much higher risk of KS in individuals with acquired T cell deficiencies, we conclude that STIM1 T cell deficiency precipitated the development of lethal KS in this child upon infection with HHV-8. 20876309 2010