AURKA, aurora kinase A, 6790

N. diseases: 245; N. variants: 15
Disease: Familial lichen amyloidosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0268398
Disease: Familial lichen amyloidosis
Familial lichen amyloidosis 		0.020 Biomarker disease BEFREE AURKA amplification was identified in overall 65% of PCAs (hormone naïve and treated) from patients that developed t-NEPC and in 86% of metastases. 23358695 2013
CUI: C0268398
Disease: Familial lichen amyloidosis
Familial lichen amyloidosis 		0.020 AlteredExpression disease BEFREE We discovered significant overexpression and gene amplification of AURKA and MYCN in 40% of NEPC and 5% of PCA, respectively, and evidence that that they cooperate to induce a neuroendocrine phenotype in prostate cells. 22389870 2011