AURKA, aurora kinase A, 6790

N. diseases: 245; N. variants: 15
Disease: Adult Liposarcoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0278608
Disease: Adult Liposarcoma
Adult Liposarcoma 		0.020 Biomarker disease BEFREE Expression profile‑driven discovery of AURKA as a treatment target for liposarcoma. 31485600 2019
CUI: C0278608
Disease: Adult Liposarcoma
Adult Liposarcoma 		0.020 Biomarker disease BEFREE Overall, our study showed that selinexor treatment restored tumor suppressive function of IGFBP5 and inhibited aurora kinase A and B in liposarcoma cells supporting the usefulness of selinexor as a potential therapeutic strategy for the treatment of this cancer. 27893412 2017