STK11, serine/threonine kinase 11, 6794

N. diseases: 372; N. variants: 145
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011847
Disease: Diabetes
Diabetes
0.040 GeneticVariation disease BEFREE Based on the previously reported association between the STK11 gene and diabetes, we aimed to investigate whether the rs8111699 polymorphism in STK11 has any role in gestation diabetes in Saudi women. 26345094 2015
CUI: C0011847
Disease: Diabetes
Diabetes
0.040 GeneticVariation disease BEFREE A common gene variant in STK11 is associated with metabolic risk markers and diabetes during gestation. 23706335 2013
CUI: C0011847
Disease: Diabetes
Diabetes
0.040 Biomarker disease BEFREE We tested the therapeutic potential of metabolic drugs in NSCLC and identified phenformin, a mitochondrial inhibitor and analog of the diabetes therapeutic metformin, as selectively inducing apoptosis in LKB1-deficient NSCLC cells. 23352126 2013
CUI: C0011847
Disease: Diabetes
Diabetes
0.040 Biomarker disease BEFREE Recent studies suggest the involvement of LKB1 also in more common human disorders including diabetes and in a significant fraction of lung adenocarcinomas. 17010524 2007