STK11, serine/threonine kinase 11, 6794

N. diseases: 372; N. variants: 145
Disease: polyp benign ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0747742
Disease: polyp benign
polyp benign 		0.020 GeneticVariation disease BEFREE Germline mutations in the STK11 gene (encoding LKB1) are the cause of the Peutz-Jeghers syndrome, which is characterized by benign polyps in the intestine and a higher risk for the patients to develop intestinal and extraintestinal tumors. 29540834 2018
CUI: C0747742
Disease: polyp benign
polyp benign 		0.020 AlteredExpression disease BEFREE Inactivation of LKB1 is associated with progression of PJS and transformation of benign polyps into malignant tumors. 17761947 2007