STK11, serine/threonine kinase 11, 6794

N. diseases: 372; N. variants: 145
Disease: Sporadic Breast Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1336076
Disease: Sporadic Breast Carcinoma
Sporadic Breast Carcinoma 		0.040 AlteredExpression disease BEFREE Approximately 30% of sporadic breast cancer samples express low levels of LKB1. 17114342 2006
CUI: C1336076
Disease: Sporadic Breast Carcinoma
Sporadic Breast Carcinoma 		0.040 AlteredExpression disease BEFREE The low expression of LKB1/STK11 in sporadic breast cancer is significantly associated with shorter survival. 15714005 2004
CUI: C1336076
Disease: Sporadic Breast Carcinoma
Sporadic Breast Carcinoma 		0.040 GeneticVariation disease BEFREE To investigate the function of the LKB1 gene in sporadic breast cancer, we reintroduced LKB1 into breast cancer cell lines which lack the LKB1 gene. 12114407 2002
CUI: C1336076
Disease: Sporadic Breast Carcinoma
Sporadic Breast Carcinoma 		0.040 GeneticVariation disease BEFREE The results indicate that mutations in LKB1 do not play an important role in the development of sporadic breast cancer. 9537235 1998