STRN, striatin, 6801

N. diseases: 30; N. variants: 6
Disease: Thyroid Neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.020 AlteredExpression disease BEFREE Transgenic mice with thyroid-specific expression of STRN-ALK developed poorly differentiated thyroid tumors by the age of 12 months in 22% of mice without goitrogen treatment and in 36% of mice with goitrogen treatment. 30125543 2018
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.020 Biomarker disease BEFREE Our data demonstrate that STRN-ALK fusion occurs in a subset of patients with highly aggressive types of thyroid cancer and provide initial evidence suggesting that it may represent a therapeutic target for these patients. 24613930 2014