SULT1A1, sulfotransferase family 1A member 1, 6817

N. diseases: 122; N. variants: 13
Disease: Malignant neoplasm of esophagus ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus 		0.020 GeneticVariation disease BEFREE The SULT1A1*2/*2 genotype in combination with the CYP3A5 heterozygous genotypes was associated with significantly increased risk for OC (AOR, 3.60; P=0.001) with the risk being even higher among smokers compared with non-smokers. 16272171 2006
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus 		0.020 GeneticVariation disease BEFREE Our findings suggest that the SULT1A1 his(213) allele is important in the development of esophageal cancer in men. 12455060 2003