SYK, spleen associated tyrosine kinase, 6850

N. diseases: 229; N. variants: 7
Disease: Arthritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003864
Disease: Arthritis
Arthritis 		0.010 Biomarker disease BEFREE Our results indicated that Syk deficiency rendered mice completely unresponsive to immune activation by anti-collagen antibodies with disabling one pathway of FcγR-mediated signaling that was crucial for arthritis induction. 22914861 2012