SYK, spleen associated tyrosine kinase, 6850

N. diseases: 229; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.040 Biomarker group BEFREE Based on the known interaction between SYK and mammalian target of rapamycin (mTOR) signaling in lymphoma, we hypothesized that SYK may regulate mTOR signaling in AML. 23535559 2013
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.040 Biomarker group BEFREE Together, these findings provide insights into cellular pathways required for lymphoma cell growth and support the rationale for considering SYK inhibition as a potentially useful therapy for DLBCL. 22025527 2011
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.040 AlteredExpression group LHGDN Protein tyrosine phosphatase receptor-type O truncated (PTPROt) regulates SYK phosphorylation, proximal B-cell-receptor signaling, and cellular proliferation. 16888096 2006
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.040 Biomarker group LHGDN Expression pattern of intracellular leukocyte-associated proteins in primary mediastinal B cell lymphoma. 15744341 2005