SYK, spleen associated tyrosine kinase, 6850

N. diseases: 229; N. variants: 7
Disease: Severe Combined Immunodeficiency ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0085110
Disease: Severe Combined Immunodeficiency
Severe Combined Immunodeficiency 		0.020 Biomarker disease BEFREE Unexpectedly, SYK-11L(+) was found to have no tumorigenicity in SCID mice. 15132768 2004
CUI: C0085110
Disease: Severe Combined Immunodeficiency
Severe Combined Immunodeficiency 		0.020 AlteredExpression disease BEFREE Although SYK has not been linked to a human disease, defective expression of the closely related T-cell tyrosine kinase ZAP-70 has been associated with severe combined immunodeficiency. 11494125 2001