SYK, spleen associated tyrosine kinase, 6850

N. diseases: 229; N. variants: 7
Disease: Adult Burkitt Lymphoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0278764
Disease: Adult Burkitt Lymphoma
Adult Burkitt Lymphoma 		0.020 AlteredExpression disease BEFREE SYK inhibition lowers viability and Mcl-1 protein levels in Burkitt's lymphoma cell lines. 29740433 2018
CUI: C0278764
Disease: Adult Burkitt Lymphoma
Adult Burkitt Lymphoma 		0.020 AlteredExpression disease BEFREE By global proteomic and phosphoproteomic profiling, we show that, in BL, HSP90 inhibition compromises the activity of the pivotal B-cell antigen receptor (BCR)-proximal effector spleen tyrosine kinase (SYK), which we identified as an HSP90 client protein. 28064214 2017