SYK, spleen associated tyrosine kinase, 6850

N. diseases: 229; N. variants: 7
Disease: Childhood Lymphoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1332979
Disease: Childhood Lymphoma
Childhood Lymphoma 		0.020 Biomarker disease BEFREE Based on the known interaction between SYK and mammalian target of rapamycin (mTOR) signaling in lymphoma, we hypothesized that SYK may regulate mTOR signaling in AML. 23535559 2013
CUI: C1332979
Disease: Childhood Lymphoma
Childhood Lymphoma 		0.020 Biomarker disease BEFREE Together, these findings provide insights into cellular pathways required for lymphoma cell growth and support the rationale for considering SYK inhibition as a potentially useful therapy for DLBCL. 22025527 2011