Mood Disorders
|
0.370 |
Biomarker
|
group |
PSYGENET |
Method We investigated the associations between SSEPs and polymorphisms within candidate genes of the serotonergic, GABAergic as well as the substance P system in subjects at high risk for affective disorders.
|
22225676 |
2013 |
Mood Disorders
|
0.370 |
GeneticVariation
|
group |
BEFREE |
These results suggest that the ACE I/D polymorphism is one of the genetic factors for an interindividual variability of brain SP levels, and that the ACE polymorphism may contribute to the susceptibility to affective disorders.
|
8931914 |
1996 |
Mood Disorders
|
0.370 |
Biomarker
|
group |
BEFREE |
In this study, we used macroarrays to investigate the differential gene expression profile induced by SP, particularly of genes which have been shown to be involved in the pathophysiology of affective disorders.
|
16806114 |
2006 |
Mood Disorders
|
0.370 |
Biomarker
|
group |
PSYGENET |
In this study, we used macroarrays to investigate the differential gene expression profile induced by SP, particularly of genes which have been shown to be involved in the pathophysiology of affective disorders.
|
16806114 |
2006 |
Mood Disorders
|
0.370 |
Biomarker
|
group |
BEFREE |
The results confirm an involvement of the tachykinins in psychiatric disorders, suggesting there is a generalized impairment of the SP system in the amygdala in mood disorders and schizophrenia rather than this being a disease-related phenomenon.
|
15845098 |
2005 |
Mood Disorders
|
0.370 |
Biomarker
|
group |
PSYGENET |
More recently, the neuropeptide substance P (SP) and its receptor (the neurokinin-1 receptor [NK1R]) have been implicated in the pathophysiology of affective disorders, including depression.
|
12562138 |
2002 |
Mood Disorders
|
0.370 |
Biomarker
|
group |
PSYGENET |
Results from preclinical and human studies implicate SP and its pathway in the pathophysiology of mood disorders.
|
15927090 |
2005 |
Mood Disorders
|
0.370 |
Biomarker
|
group |
BEFREE |
This review focuses on the role of SP in the pathogenesis of affective disorders.
|
12692775 |
2003 |
Mood Disorders
|
0.370 |
Biomarker
|
group |
PSYGENET |
The results confirm an involvement of the tachykinins in psychiatric disorders, suggesting there is a generalized impairment of the SP system in the amygdala in mood disorders and schizophrenia rather than this being a disease-related phenomenon.
|
15845098 |
2005 |
Mood Disorders
|
0.370 |
Biomarker
|
group |
BEFREE |
Method We investigated the associations between SSEPs and polymorphisms within candidate genes of the serotonergic, GABAergic as well as the substance P system in subjects at high risk for affective disorders.
|
22225676 |
2013 |
Mood Disorders
|
0.370 |
Biomarker
|
group |
BEFREE |
Results from preclinical and human studies implicate SP and its pathway in the pathophysiology of mood disorders.
|
15927090 |
2005 |
Mood Disorders
|
0.370 |
Biomarker
|
group |
BEFREE |
Comparison of the frequency of the genotypes deduced from the polymorphic alleles of gastrin-releasing peptide, NPY, somatostatin and substance P in normals vs patients with either AD or schizophrenia suggests the absence of association.
|
2894462 |
1987 |