TAC1, tachykinin precursor 1, 6863

N. diseases: 478; N. variants: 0
Disease: Multiple Sclerosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.040 GeneticVariation disease BEFREE The TRPV1+ neurovascular complex defining the blood-CNS barriers promoted invasion of pathogenic lymphocytes without the contribution of TRPV1-dependent neuropeptides such as substance P. In MS patients, we found a selective risk-association of the missense rs877610 TRPV1 single nucleotide polymorphism (SNP) in primary progressive disease. 23689362 2013
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.040 GeneticVariation disease BEFREE Our data advocate a need for further exploration of the TAC1 gene region in MS. 17175032 2007
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.040 PosttranslationalModification disease BEFREE While independent reproduction of these data in other data sets is indicated, our work is suggestive for a role of the TAC1 gene in MS. 15729363 2005
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.040 GeneticVariation disease BEFREE Chromosome 7q21-22 and multiple sclerosis: evidence for a genetic susceptibility effect in vicinity to the protachykinin-1 gene. 11960650 2002