TAC1, tachykinin precursor 1, 6863

N. diseases: 478; N. variants: 0
Disease: Cerebrovascular accident ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		0.040 AlteredExpression group BEFREE In 40 subjects, saliva was collected within 72 h after stroke onset and salivary SP levels were measured using ELISA kit at a later date. 29185035 2018
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		0.040 Biomarker group BEFREE The tachykinin substance P (SP) increases neuronal excitability, participates in homeostatic control, but induces brain oedema after stroke or trauma. 30518958 2018
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		0.040 Biomarker group BEFREE In addition, the cardiovascular variable, pulse distension (a surrogate for stroke volume) was improved in the neurokinin-1 receptor antagonist group during the first 6 hours of sepsis, and there was a significant reduction in loss of fluid into the intestine. 27632670 2017
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		0.040 Biomarker group BEFREE In patients with elevated LV end-diastolic pressure, an intracoronary infusion of substance P increased LV stroke volume from 72+/-13 to 91+/-16 mL (P=0.06) and LV stroke work from 67+/-11 to 90+/-15 g. m (P=0.03) and shifted the LV end-diastolic pressure-volume relation to the right. 10368118 1999