|
Endometriosis
|
0.330 |
Biomarker
|
disease |
BEFREE |
Therefore, the miR-142-3p/KLF9/VEGFA signalling pathway may be a potential target in endometriosis treatment.
|
31425004 |
2019 |
|
Endometriosis
|
0.330 |
Biomarker
|
disease |
BEFREE |
We previously demonstrated promotion of ectopic lesion establishment by Klf9 null endometrium in a mouse model of endometriosis.
|
25904015 |
2015 |
|
Endometriosis
|
0.330 |
AlteredExpression
|
disease |
BEFREE |
Eutopic endometrium from women with endometriosis had reduced expression of KLF9 mRNA together with those of PGR-B, WNT4, WNT2, and DKK1.
|
22259059 |
2012 |
|
Endometriosis
|
0.330 |
Biomarker
|
disease |
CTD_human |
Molecular evidence for differences in endometrium in severe versus mild endometriosis.
|
21063030 |
2011 |
|
Thyroid Diseases
|
0.310 |
Biomarker
|
group |
BEFREE |
Our findings suggest that the TR-KLF9 axis is responsible for the hematopoietic dysfunction and might be exploited for the development of novel therapeutic interventions for thyroid diseases.
|
28972010 |
2017 |
|
Thyroid Diseases
|
0.310 |
Biomarker
|
group |
CTD_human |
Monitoring of deiodinase deficiency based on transcriptomic responses in SH-SY5Y cells.
|
23397585 |
2013 |
|
Heart Failure, Diastolic
|
0.300 |
Biomarker
|
disease |
CTD_human |
In Silico Analysis of Differential Gene Expression in Three Common Rat Models of Diastolic Dysfunction.
|
29556499 |
2018 |
|
Body Weight
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations.
|
22344221 |
2012 |
|
Endometrioma
|
0.300 |
Biomarker
|
disease |
CTD_human |
Molecular evidence for differences in endometrium in severe versus mild endometriosis.
|
21063030 |
2011 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Krüppel-like factor 9 (KLF9) has prodifferentiation and tumor suppression functions in several types of cancers.
|
31782614 |
2020 |
|
Carcinogenesis
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
In addition, upregulation of miR-889 promotes tumorigenesis in vitro, and KLF9 protein levels are also reduced.
|
30849540 |
2019 |
|
Carcinogenesis
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
In addition, up-regulation of miR-660-5p promoted tumorigenesis in vivo, and the protein level of KLF9 also decreased in xenografts.
|
31128012 |
2019 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Krüppel-like factor 9 (KLF9) plays critical roles in several types of tumor.
|
29107105 |
2018 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Kruppel-like factor 9 (KLF9), a transcription factor, is critical for the inhibition of growth and development of tumors, whereas its effects in pancreatic cancer remains unclear.
|
30542730 |
2018 |
|
Carcinogenesis
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
Knocking down the expression of KLF9 also promoted the tumorigenesis in the PDAC mouse xneograft model.
|
29621541 |
2018 |
|
mathematical ability
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.
|
30038396 |
2018 |
|
Leukemia, Myelocytic, Acute
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.
|
27903959 |
2017 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
KLF9 is the core effector protein that might suppress tumor growth.
|
27956179 |
2017 |
|
Carcinogenesis
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
Restoration of miR-141-3p suppresses the expression of the transcription factor KLF9 in PC-3 and accelerates prostate tumorigenesis via targeted binding with its 3'-UTR.
|
27956179 |
2017 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Krüppel-like factor 9 (KLF9) has been found to play suppressive roles in several types of tumor.
|
25641762 |
2016 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Krüppel-like factor 9 (KLF9) is a haploinsufficient tumor suppressor in the ApcMin/+ mouse colon by suppressing expression of ISG15, an apoptosis-inhibiting cytokine.
|
26210742 |
2015 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
In the present study, we aim to investigate the effect of lentivirus-mediated knockdown of Krüppel-like factor 9 (KLF9) on cell viability and tumor growth in ovarian cancer.
|
25216959 |
2015 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
At the molecular level, krüppel-like factor 9 (KLF9), a tumor suppressor gene, was identified as a potential target of miR-570 in lung cancer cells.
|
26045791 |
2015 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Importantly, re-constitution of KLF9 expression inhibited glioma cell proliferation and tumor growth in vivo.
|
25305446 |
2015 |
|
Carcinogenesis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Results show KLF9 to be a haploinsufficient suppressor of colon tumorigenesis in Apc(Min/+) mice in part, by repression of ISG15 and the latter's antiapoptotic function.
|
26210742 |
2015 |