TAGLN, transgelin, 6876

N. diseases: 131; N. variants: 4
Disease: Dissection of aorta ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0340643
Disease: Dissection of aorta
Dissection of aorta 		0.030 Biomarker disease BEFREE SM22α-deficient mice demonstrated pregnancy-induced aortic dissection, and SM22α deficiency worsened aortic aneurysm in Fbn1C1039G/+ (Marfan) mice, validating this gene product as a TAA effector. 29515022 2018
CUI: C0340643
Disease: Dissection of aorta
Dissection of aorta 		0.030 AlteredExpression disease BEFREE SM22 was significantly downregulated in the media of AD samples compared with controls (P < .05). 27320219 2017
CUI: C0340643
Disease: Dissection of aorta
Dissection of aorta 		0.030 Biomarker disease BEFREE To examine the expression of interleukin-6 (IL-6), interferon-γ (IFN-γ), smooth muscle 22α (SM22α), and matrix metalloproteinase-2 (MMP-2) and their possible roles in aortic dissections (AD). 28239811 2017