Disease: Steatohepatitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2711227
Disease: Steatohepatitis
Steatohepatitis 		0.040 Biomarker disease BEFREE We further found that the binding of Dusp26 to transforming growth factor beta-activated kinase 1 (TAK1) to block the phosphorylation of TAK1 regulated the TAK1-p38/c-Jun NH2-terminal kinase signaling axis to alleviate hepatic steatosis and metabolic disturbance. 30582764 2019
CUI: C2711227
Disease: Steatohepatitis
Steatohepatitis 		0.040 Biomarker disease BEFREE The E3 ligase tripartite motif 8 targets TAK1 to promote insulin resistance and steatohepatitis. 27981609 2017
CUI: C2711227
Disease: Steatohepatitis
Steatohepatitis 		0.040 Biomarker disease BEFREE Thus, TAK1 regulation of SREBP critically contributes to the maintenance of liver homeostasis to prevent steatosis, which is a potentially important mechanism to prevent HCC development. 26973245 2016
CUI: C2711227
Disease: Steatohepatitis
Steatohepatitis 		0.040 Biomarker disease BEFREE In conclusion, hepatocyte TRAF3 promotes HFD-induced or genetic hepatic steatosis in a TAK1-dependent manner. 26882989 2016