TAT, tyrosine aminotransferase, 6898

N. diseases: 230; N. variants: 28
Disease: Septicemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036690
Disease: Septicemia
Septicemia 		0.030 Biomarker disease BEFREE Two well-known Cx43 mimetic peptides, the GAP26 and TAT-GAP19, divergently affected macrophage hemichannel activities in vitro, and differentially altered the outcome of lethal sepsis in vivo. 29317708 2018
CUI: C0036690
Disease: Septicemia
Septicemia 		0.030 GeneticVariation disease BEFREE Haplotype TAT (rs2972164, rs4684846, and rs17036188) was associated with increased sepsis risk (1.66 [1.03-2.67], P = .038). 29055064 2018
CUI: C0036690
Disease: Septicemia
Septicemia 		0.030 Biomarker disease BEFREE In conclusion, TAT-conjugated antiapoptotic Bcl-2-like peptides may offer a novel therapy to prevent apoptosis in sepsis and improve survival. 16622015 2006