TBX1, T-box transcription factor 1, 6899

N. diseases: 417; N. variants: 14
Disease: Undifferentiated leukemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1378511
Disease: Undifferentiated leukemia
Undifferentiated leukemia 		0.020 Biomarker disease BEFREE Further, corresponding to the morphological changes of nucleolus in number and size, these highly proliferating SSEA1 cells demonstrated coexpression of either D2-40 or the mesodermal marker Scl (stem cell leukemia), brachyury, and Flk-1 (vascular endothelial growth factor-2), respectively, indicative of the neoplasmtic transformation into the stromal or vascular cells. 21811099 2011
CUI: C1378511
Disease: Undifferentiated leukemia
Undifferentiated leukemia 		0.020 Biomarker disease BEFREE Consistent with an embryologically derived hemangioblast, the neoplastic cells demonstrated coexpression of the mesodermal markers brachyury, Flk-1 (vascular endothelial growth factor-2), and stem cell leukemia (Scl). 17298169 2007