TBX2, T-box transcription factor 2, 6909

N. diseases: 152; N. variants: 11
Disease: Preexcitation Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0032915
Disease: Preexcitation Syndrome
Preexcitation Syndrome 		0.010 AlteredExpression disease BEFREE Here we show that myocardium-specific inactivation of T-box 2 (Tbx2), a transcription factor essential for atrioventricular canal patterning, leads to the formation of fast-conducting accessory pathways, malformation of the annulus fibrosus, and ventricular preexcitation in mice. 21266775 2011