ZEB1, zinc finger E-box binding homeobox 1, 6935

N. diseases: 310; N. variants: 16
Disease: ovarian neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.380 Biomarker disease BEFREE ZEB1 reversed partial roles of miR-1271 on viability and invasion in OC. 31695412 2019
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.380 Biomarker disease BEFREE <b>Conclusions:</b> As both Snail and ZEB1 are crucial inducers of epithelial-to-mesenchymal transition (EMT), our data suggested that CD44 may be crucial for the EMT process of ovarian cancer. 31497537 2019
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.380 Biomarker disease BEFREE MiR-1236-3p reportedly plays a tumor-suppressor role in OC by targeting zinc finger E-box binding homeobox 1 (ZEB1). 30965236 2019
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.380 Biomarker disease BEFREE Meanwhile, we found that silencing miR-101 promoted cell migration, whereas the overexpression of miR-101 suppressed EMT and cell migration in OvCa cell lines through the regulation of ZEB1. 30098599 2018
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.380 Biomarker disease BEFREE ZEB1 Promotes Chemoresistance to Cisplatin in Ovarian Cancer Cells by Suppressing SLC3A2. 30481785 2018
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.380 Biomarker disease BEFREE Here we describe that TAMs require ZEB1 for their tumor-promoting and chemotherapy resistance functions in a mouse model of ovarian cancer. 29038174 2017
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.380 Biomarker disease BEFREE GRHL2-miR-200-ZEB1 maintains the epithelial status of ovarian cancer through transcriptional regulation and histone modification. 26887977 2016
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.380 Biomarker disease BEFREE Taken together, our results indicate that miR-1236-3p regulates ovarian cancer metastasis by directly targeting ZEB1, and it may play an important role in the diagnosis and treatment of ovarian cancer. 24573236 2014
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.380 Biomarker disease CTD_human Expression of the ZEB1 (deltaEF1) transcription factor in human: additional insights. 18622689 2008