|
Anemia, Megaloblastic
|
0.300 |
Biomarker
|
disease |
CTD_human |
Megaloblastic anemia after anticonvulsive therapy.
|
4627864 |
1972 |
|
Blood Protein Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genomic atlas of the human plasma proteome.
|
29875488 |
2018 |
|
VITAMIN B12 MEASUREMENT
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
GWAS identifies population-specific new regulatory variants in FUT6 associated with plasma B12 concentrations in Indians.
|
28334792 |
2017 |
|
VITAMIN B12 MEASUREMENT
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genetic Associations with Plasma B12, B6, and Folate Levels in an Ischemic Stroke Population from the Vitamin Intervention for Stroke Prevention (VISP) Trial.
|
25147783 |
2014 |
|
VITAMIN B12 MEASUREMENT
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway.
|
19744961 |
2009 |
|
VITAMIN B12 MEASUREMENT
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway.
|
19744961 |
2009 |
|
Transcobalamin I Deficiency
|
0.100 |
CausalMutation
|
disease |
CLINVAR |
|
|
|
|
NEUROTICISM
|
0.040 |
GeneticVariation
|
disease |
BEFREE |
In particular, high serum TSH was strongly associated with higher Persistence and Self-Directedness, and negatively correlated with Harm Avoidance on the TCI-140 and Neuroticism on the NEO-FFI, thus representing a more adaptive personality profile.
|
29102897 |
2018 |
|
NEUROTICISM
|
0.040 |
Biomarker
|
disease |
BEFREE |
Studies that used the TCI to assess Harm Avoidance or the EPQ to assess Neuroticism have found no association with the 5-HTTLPR.
|
19199283 |
2009 |
|
NEUROTICISM
|
0.040 |
Biomarker
|
disease |
BEFREE |
Contrasts between the S/S and L/L groups were significant for TCI/TPQ harm avoidance studies (P=0.0024) but not NEO neuroticism (P=0.9757).
|
15599377 |
2005 |
|
NEUROTICISM
|
0.040 |
Biomarker
|
disease |
BEFREE |
When the analysis was stratified by inventory type, there was a significant association between 5-HTTLPR and NEO neuroticism (P = 0.000016), a non-significant association between 5-HTTLPR and TCI/TPQ harm avoidance (P = 0.166), and no association between 5-HTTLPR and other anxiety-related personality traits (P = 0.944).
|
15108187 |
2004 |
|
Malignant Neoplasms
|
0.030 |
Biomarker
|
group |
BEFREE |
Haptocorrin was significantly higher in those with cancer, mainly among patients with adenocarcinoma (<i>n</i> = 94).
|
31738590 |
2020 |
|
Coinfection
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
It was observed that 42.8% of the dogs tested positive for T. evansi and 14.3% presented mixed infection; 15% of the triatomines tested positive for flagellates identified as T. cruzi TCI (3 specimens), T. cruzi TCI, and T. rangeli (1 specimen), and one with T. cruzi TCV.
|
31778401 |
2019 |
|
Neoplasms
|
0.030 |
Biomarker
|
group |
BEFREE |
The study investigates the vaccination capacity of TCI in combination with the checkpoint inhibitor CTLA-4 in matters of primary response, memory formation and tumor protection and characterizes the role of regulatory T cells (Tregs).
|
28666747 |
2017 |
|
Neoplasms
|
0.030 |
AlteredExpression
|
group |
BEFREE |
<b>Results:</b> TCN1 overexpression was significantly related to advanced post-treatment tumor (T3, T4; <i>p</i><0.001) and nodal status (N1, N2; <i>p</i><0.001), vascular invasion (<i>p</i>=0.003) and inferior tumor regression grade (<i>p</i> < 0.001).
|
28638446 |
2017 |
|
Malignant Neoplasms
|
0.030 |
AlteredExpression
|
group |
BEFREE |
Although expression of TCN1 alone was present in all malignant and 34 of 40 (85.0%) borderline tumors, a combined panel with HOXB13 excluded some benign cases and was a better discriminant for a significant proportion of borderline and malignant tumors.
|
21574054 |
2012 |
|
Neoplasms
|
0.030 |
AlteredExpression
|
group |
BEFREE |
Although expression of TCN1 alone was present in all malignant and 34 of 40 (85.0%) borderline tumors, a combined panel with HOXB13 excluded some benign cases and was a better discriminant for a significant proportion of borderline and malignant tumors.
|
21574054 |
2012 |
|
Coinfection
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
The most frequent T. cruzi genotypes found in mothers studied during pregnancy were TCI and TCIId, either alone or in mixed infections.
|
21249297 |
2010 |
|
Malignant Neoplasms
|
0.030 |
Biomarker
|
group |
BEFREE |
These results underscore the potential for Vpr based reagents as well as PTDs to enhance anti-tumor activity, and warrants further examination of Vpr protein and derived peptides as potential therapeutic agents against progressive cell proliferative diseases such as cancer.
|
19029839 |
2009 |
|
Coinfection
|
0.030 |
GeneticVariation
|
phenotype |
BEFREE |
In summary, our results demonstrate (i) differences in genetic diversity of C. neoformans isolates from India compared to isolates from other regions in the world; (ii) that DNA typing with the TCN-1 probe can adequately distinguish C. neoformans var. grubii strains; (iii) that TCN-1 sequences are absent in many C. neoformans var. gattii strains, supporting previous studies indicating that these strains have a limited geographical dispersal; and (iv) that human cryptococcal infection can be associated with microevolution of the infecting strain and by simultaneous coinfection with two distinct C. neoformans strains.
|
16272511 |
2005 |
|
Primary malignant neoplasm
|
0.020 |
Biomarker
|
group |
BEFREE |
Haptocorrin was significantly higher in those with cancer, mainly among patients with adenocarcinoma (<i>n</i> = 94).
|
31738590 |
2020 |
|
Colorectal Carcinoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
<b>Purpose</b>: The recent success of anti-PD1 antibody in metastatic colorectal cancer (CRC) patients with microsatellite instability (MSI), known to be associated with an upregulated Th1/Tc1 gene signature, provides new promising therapeutic strategies.
|
30906656 |
2019 |
|
Mental Depression
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
A wide neuropsychiatric battery was employed including the following: symptoms checklist 90-R (SCL-90-R), Toronto alexithymia scale (TAS-20), Hamilton anxiety rating scale (HAMA), Beck depression inventory (BDI II), dissociative experiences scale (DES), traumatic experience checklist (TEC), somatoform dissociation questionnaire (SDQ-20), and temperament and character inventory-revised (TCI-R).
|
29092782 |
2018 |
|
Depressive disorder
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
A wide neuropsychiatric battery was employed including the following: symptoms checklist 90-R (SCL-90-R), Toronto alexithymia scale (TAS-20), Hamilton anxiety rating scale (HAMA), Beck depression inventory (BDI II), dissociative experiences scale (DES), traumatic experience checklist (TEC), somatoform dissociation questionnaire (SDQ-20), and temperament and character inventory-revised (TCI-R).
|
29092782 |
2018 |
|
Depressed mood
|
0.020 |
GeneticVariation
|
phenotype |
BEFREE |
A wide neuropsychiatric battery was employed including the following: symptoms checklist 90-R (SCL-90-R), Toronto alexithymia scale (TAS-20), Hamilton anxiety rating scale (HAMA), Beck depression inventory (BDI II), dissociative experiences scale (DES), traumatic experience checklist (TEC), somatoform dissociation questionnaire (SDQ-20), and temperament and character inventory-revised (TCI-R).
|
29092782 |
2018 |