BTK, Bruton tyrosine kinase, 695

N. diseases: 290; N. variants: 85
Disease: Malignant tumor of colon ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.030 Biomarker disease BEFREE BTK inhibitors synergise with 5-FU to treat drug-resistant TP53-null colon cancers. 31518438 2020
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.030 Biomarker disease BEFREE The goal of the present study was to assess the effects of combination therapy with erythropoietin β (Epo) and LFM-A13 (Btk inhibitor) on colon cancer in in vitro and in vivo models. 29160911 2018
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.030 AlteredExpression disease BEFREE A novel oncogenic BTK isoform is overexpressed in colon cancers and required for RAS-mediated transformation. 26804170 2016