BTK, Bruton tyrosine kinase, 695

N. diseases: 233; N. variants: 6
Disease: Kidney Diseases ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases 		0.020 Biomarker group BEFREE A separate experiment was performed in the MRL/lpr strain to assess the ability of BI-BTK-1 to reverse established kidney disease. 30339790 2018
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases 		0.020 Biomarker group BEFREE These findings reveal the mechanism through which a selective Btk inhibitor blocks murine autoimmune kidney disease, highlighting pathway activity that may translate to human SLE. 28405610 2017