BTK, Bruton tyrosine kinase, 695

N. diseases: 233; N. variants: 6
Disease: Breast Carcinoma ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.320 Biomarker disease BEFREE In this study, we show that recently developed inhibitors of BTK, such as ibrutinib (PCI-32765), AVL-292, and CGI-1746, reduce breast cancer cell survival and prevent drug-resistant clones from arising. 27256378 2016
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.320 AlteredExpression disease BEFREE Our results surprisingly show that BTK is expressed in several breast cancer cell lines and tumors. 23913792 2013