BTK, Bruton tyrosine kinase, 695

N. diseases: 290; N. variants: 85
Disease: Invasive Fungal Infections ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1262313
Disease: Invasive Fungal Infections
Invasive Fungal Infections 		0.020 Biomarker group BEFREE The spectrum and severity of IFIs often observed in these patients implies the presence of a complex immunodeficiency that may not be solely attributed to mere inhibition of Bruton tyrosine kinase. 29029010 2018
CUI: C1262313
Disease: Invasive Fungal Infections
Invasive Fungal Infections 		0.020 Biomarker group BEFREE <i>In vitro</i> studies indicate Bruton tyrosine kinase inhibition impairs phagocyte function and offer a mechanism for the apparent association between ibrutinib and invasive fungal infections. 30021735 2018