TRB, T cell receptor beta locus, 6957

N. diseases: 49; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.050 Biomarker disease LHGDN Clonally expanded CD4+CD28null T cells in rheumatoid arthritis use distinct combinations of T cell receptor BV and BJ elements. 12594835 2003
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.050 GeneticVariation disease BEFREE Our previous studies have disclosed that the peripheral T cell receptor beta (TCRB) gene repertoires of RA monozygotic twins were similar. 9409647 1997
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.050 GeneticVariation disease BEFREE These linkage studies provide no significant evidence of a major germline-encoded TCRA or TCRB component of susceptibility to RA. 9336413 1997
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.050 GeneticVariation disease BEFREE Ten TCRB allelic polymorphisms were analyzed from 3 groups of white women: 112 with RA, 72 with systemic lupus erythematosus, and 70 healthy controls.All participants were also HLA typed. 8651986 1996
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.050 GeneticVariation disease BEFREE These results argue against the hypothesis that TCRB polymorphisms play a crucial role in the susceptibility for RA. 7979596 1994