TDG, thymine DNA glycosylase, 6996

N. diseases: 34; N. variants: 2
Disease: Germ Cell Cancer ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0740345
Disease: Germ Cell Cancer
Germ Cell Cancer 		0.010 Biomarker disease BEFREE A meta-analysis of gene expression data of germ cell cancer tissues and corresponding cell lines demonstrates high expression of TET1 and the DNA glycosylase TDG, suggesting that germ cell cancers utilize the oxidation pathway for active DNA demethylation. 24386123 2013